Abstract. This paper provides the results of the study of a spatial flow in a low-flow stage of a SVD-22 centrifugal compressor of computational fluid dynamics methods using the Ansys CFX 14.0 software package. Low flow stages are used as the last stages of multistage centrifugal compressors. Such multistage compressors are widely used in boosting compressor stations for natural gas, in chemical industries. The flow features  in low-flow stages require independent research. This is due to the fact that the developed techniques for designing centrifugal compressor stages are created for medium-flow and high-flow stages and do not apply to low-flow stages. Generally at manufacturing new centrifugal compressors, it is impossible to make a control measurement of the parameters of the working process inside the flow path elements. Computational fluid dynamics methods are widely used to overcome this difficulties. However verification and validation of CFD methods are necessary for accurate modeling of the workflow. All calculations were conducted on one of the SPbPU clusters. Parameters of one cluster node: AMD Opteron 280 — 2 cores, 8GB RAM. The calculations were conducted using 4 nodes (HP MPI Distributed Parallel startup type) with their full load by parallelizing processes on each node.